Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.53 |
| ▸ | DRD1 | P21728 | 2/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4667624 | 0.88 | SIGMAR1 (0.68) | MEN1KMT2ASIGMAR1CYP2D6SLC6A2 | |
| SCHEMBL8097776 | 0.84 | CHRNA7 (0.79) | CHRNA7MEN1KMT2ASIGMAR1CYP2D6 | |
| SCHEMBL10356303 | 0.81 | SLC6A4 (0.70) | MEN1KMT2ASIGMAR1CYP2D6SLC6A2 | |
| Hydrochloric Acid SCHEMBL10552395 | 0.80 | SLC6A4 (0.68) | MEN1KMT2ASIGMAR1CYP2D6SLC6A2 | |
| SCHEMBL10357800 | 0.79 | SIGMAR1 (0.81) | MEN1KMT2ASIGMAR1CYP2D6SLC6A2 | |
| SCHEMBL10552209 | 0.78 | CHRNA7 (0.66) | CHRNA7MEN1KMT2ASIGMAR1CYP2D6 | |
| SCHEMBL4667597 | 0.78 | CYP2D6 (0.76) | CHRNA7MEN1KMT2ACYP2D6SLC6A2 | |
| SCHEMBL7423150 | 0.78 | CHRNA7 (0.65) | CHRNA7MEN1KMT2ASIGMAR1CYP2D6 | |
| SCHEMBL7006203 | 0.78 | TDP1 (0.60) | MEN1KMT2ACYP2D6SLC6A2SLC6A4 | |
| SCHEMBL4667575 | 0.78 | CYP2D6 (0.58) | MEN1KMT2ASIGMAR1CYP2D6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1930308-A1 | Pharmaceutical agents for the treatment of cerebral amyloidosis | NYMOX CORPORATION (CA) | 2008-06-11 | — | — | EP | disclosed |
| EP-1930308-A1 | Pharmaceutical agents for the treatment of cerebral amyloidosis | NYMOX CORPORATION (CA) | 2008-06-11 | — | — | EP | disclosed |
| EP-0983222-B1 | PHARMACEUTICAL AGENTS FOR THE TREATMENT OF CEREBRAL AMYLOIDOSIS | NYMOX CORP (CA) | 2007-11-28 | — | — | EP | disclosed |
| EP-0983222-B1 | PHARMACEUTICAL AGENTS FOR THE TREATMENT OF CEREBRAL AMYLOIDOSIS | NYMOX CORP (CA) | 2007-11-28 | — | — | EP | disclosed |