Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | NQO2 | P16083 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30969485 | 1.00 | TDP1 (0.65) | TDP1NQO2KMT2AMAPTCYP2A6 | |
| SCHEMBL7698365 | 0.84 | NQO2 (0.50) | TDP1NQO2KMT2AMAPTCYP2A6 | |
| SCHEMBL13156487 | 0.82 | NQO2 (0.88) | TDP1NQO2KMT2AMAPTCYP2A6 | |
| SCHEMBL23024890 | 0.80 | KDM4E (0.74) | TDP1NQO2KMT2AMAPTALDH1A1 | |
| SCHEMBL29451077 | 0.79 | TDP1 (1.00) | TDP1NQO2KMT2AMAPTALDH1A1 | |
| SCHEMBL116696 | 0.79 | TDP1 (1.00) | TDP1NQO2KMT2AMAPTALDH1A1 | |
| SCHEMBL11540011 | 0.78 | TDP1 (0.56) | TDP1NQO2KMT2AMAPTALDH1A1 | |
| SCHEMBL29237003 | 0.77 | MAPT (0.56) | TDP1NQO2KMT2AMAPTCYP2A6 | |
| Benzo[B]Phenazine SCHEMBL5481172 | 0.77 | NQO2 (1.00) | TDP1NQO2KMT2AMAPTALDH1A1 | |
| SCHEMBL2247546 | 0.77 | NQO2 (0.68) | TDP1NQO2KMT2AMAPTCYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | claimed |
| CN-117942786-A | Preparation method of nanofiltration membrane and nanofiltration membrane prepared by same | 沃顿科技股份有限公司 | 2024-04-30 | — | — | CN | disclosed |
| EP-3325486-B1 | POLYNITROGEN COMPOUNDS AND USES THEREOF AS FLUORESCENT CHROMOPHORES | UNIV ORLEANS (FR) | 2023-05-24 | — | — | EP | disclosed |
| EP-3325486-B1 | POLYNITROGEN COMPOUNDS AND USES THEREOF AS FLUORESCENT CHROMOPHORES | UNIV ORLEANS (FR) | 2023-05-24 | — | — | EP | disclosed |
| US-10954436-B2 | Polynitrogen compounds and uses thereof as fluorescent chromophores | UNIVERSITE D'ORLEANS (FR) | 2021-03-23 | — | — | US | disclosed |
| US-10954436-B2 | Polynitrogen compounds and uses thereof as fluorescent chromophores | UNIVERSITE D'ORLEANS (FR) | 2021-03-23 | — | — | US | disclosed |
| US-20180194997-A1 | POLYNITROGEN COMPOUNDS AND USES THEREOF AS FLUORESCENT CHROMOPHORES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-07-12 | — | — | US | disclosed |
| US-20180194997-A1 | POLYNITROGEN COMPOUNDS AND USES THEREOF AS FLUORESCENT CHROMOPHORES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-07-12 | — | — | US | disclosed |
| EP-3325486-A1 | POLYNITROGEN COMPOUNDS AND USES THEREOF AS FLUORESCENT CHROMOPHORES | Universite D'Orleans (FR) | 2018-05-30 | — | — | EP | disclosed |
| WO-2017013135-A1 | POLYNITROGEN COMPOUNDS AND USES THEREOF AS FLUORESCENT CHROMOPHORES | UNIVERSITE D'ORLEANS (FR) | 2017-01-26 | — | — | WO | disclosed |
| EP-1325009-B1 | AMINO-SUBSTITUTED TETRACYCLIC COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME | BRISTOL MYERS SQUIBB CO (US) | 2006-03-08 | — | — | EP | disclosed |
| US-6960585-B2 | Amino-substituted tetracyclic compounds useful as anti-inflammatory agents and pharmaceutical compositions comprising same | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-11-01 | — | — | US | disclosed |
| US-6869956-B2 | Methods of treating inflammatory and immune diseases using inhibitors of IκB kinase (IKK) | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-03-22 | — | — | US | disclosed |
| EP-1363993-A2 | METHODS OF TREATING INFLAMMATORY AND IMMUNE DISEASES USING INHIBITORS OF I$g(k)B KINASE (IKK) | Bristol-Myers Squibb Company (US) | 2003-11-26 | — | — | EP | disclosed |
| EP-1325009-A2 | AMINO-SUBSTITUTED TETRACYCLIC COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME | Bristol-Myers Squibb Company (US) | 2003-07-09 | — | — | EP | disclosed |
| US-20030022898-A1 | Methods of treating inflammatory and immune diseases using inhibitors of IkappaB kinase (IKK) | BRISTOL-MYERS SQUIBB COMPANY | 2003-01-30 | — | — | US | disclosed |
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |
| WO-2002060386-A2 | METHODS OF TREATING INFLAMMATORY AND IMMUNE DISEASES USING INHIBITORS OF IλB KINASE (IKK) | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-08-08 | — | — | WO | disclosed |
| US-20020072523-A1 | Amino-substituted tetracyclic compounds useful as anti-inflammatory agents and pharmaceutical compositions comprising same | BRISTOL-MYERS SQUIBB COMPANY | 2002-06-13 | — | — | US | disclosed |
| WO-2002028860-A2 | AMINO-SUBSTITUTED TETRACYCLIC COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180194997-A1 | POLYNITROGEN COMPOUNDS AND USES THEREOF AS FLUORESCENT CHROMOPHORES | PNN, NCL, NUCB2 | TDP1 799/4885NQO2 246/4885KMT2A 4430/4885 |
| US-20020072523-A1 | Amino-substituted tetracyclic compounds useful as anti-inflammatory agents and pharmaceutical compositions comprising same | IL4, IL4I1, MSR1 | TDP1 1986/4885NQO2 1631/4885KMT2A 2115/4885 |
| US-10954436-B2 | Polynitrogen compounds and uses thereof as fluorescent chromophores | PNN, NCL, NUCB2 | TDP1 799/4885NQO2 246/4885KMT2A 4430/4885 |
| US-20030022898-A1 | Methods of treating inflammatory and immune diseases using inhibitors of IkappaB kinase (IKK) | NFKBIA, IKBKG, IKBKB | TDP1 1259/4885NQO2 103/4885KMT2A 616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.