Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 4/20 | 0.46 |
| ▸ | RXRB | P28702 | 4/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11668400 | 0.82 | LCK (0.58) | LCKFYNTDP1SMN1; SMN2TP53 | |
| SCHEMBL701628 | 0.82 | GABRA1 (0.42) | RXRARXRBRXRGTDP1HSD17B10 | |
| SCHEMBL11346857 | 0.82 | ALDH1A1 (0.40) | TDP1SMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL134325 | 0.82 | LCK (0.64) | LCKFYNTDP1SMN1; SMN2TP53 | |
| SCHEMBL5363665 | 0.82 | CES2 (0.47) | RXRARXRBRXRGLCKFYN | |
| Hydrochloric Acid SCHEMBL6130934 | 0.81 | LCK (0.61) | LCKFYNTDP1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL10778510 | 0.81 | LCK (0.61) | LCKFYNTDP1SMN1; SMN2TP53 | |
| SCHEMBL501957 | 0.80 | RXRB (0.64) | RXRARXRBRXRGLCKFYN | |
| SCHEMBL166878 | 0.80 | RXRB (0.59) | RXRARXRBRXRGLCKFYN | |
| SCHEMBL4782469 | 0.79 | ALDH1A1 (0.51) | RXRARXRBRXRGLCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |