SCHEMBL472840

SCHEMBL472840

NC(=O)c1ccc2c(C(N)=O)c1CCCC2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.40
ALDH1A1 P00352 5/20 0.40
HSD17B10 Q99714 4/20 0.40
KDM4E B2RXH2 3/20 0.40
ALOX15 P16050 3/20 0.40
MAPK1 P28482 3/20 0.40
HPGD P15428 2/20 0.40
USP2 O75604 2/20 0.40
CASP1 P29466 1/20 0.40
CASP7 P55210 1/20 0.40
MEN1 O00255 5/20 0.39
KMT2A Q03164 5/20 0.39
NPC1 O15118 4/20 0.38
RAB9A P51151 4/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
LMNA P02545 1/20 0.38
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
MAPK8 P45983 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8864195 0.98 HSD17B10 (0.41) MAPTALDH1A1HSD17B10KDM4EALOX15
SCHEMBL18489764 0.98 HSD17B10 (0.41) MAPTALDH1A1HSD17B10KDM4EALOX15
SCHEMBL36051 0.98 HSD17B10 (0.41) MAPTALDH1A1HSD17B10KDM4EALOX15
SCHEMBL918600 0.98 HSD17B10 (0.41) MAPTALDH1A1HSD17B10KDM4EALOX15
SCHEMBL10942539 0.98 HSD17B10 (0.41) MAPTALDH1A1HSD17B10KDM4EALOX15
SCHEMBL6052857 0.96 HSD17B10 (0.40) MAPTALDH1A1HSD17B10KDM4EALOX15
SCHEMBL6466252 0.89 PARP1 (0.37) MAPTALDH1A1HSD17B10KDM4EALOX15
SCHEMBL6436615 0.84 HSD17B10 (0.41) MAPTALDH1A1HSD17B10KDM4EALOX15
SCHEMBL4566904 0.84 HSD17B10 (0.41) MAPTALDH1A1HSD17B10KDM4EALOX15
SCHEMBL1160668 0.82 HSD17B10 (0.47) MAPTALDH1A1HSD17B10KDM4EALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116421788-A Scaffolds for cell culture and tissue regeneration 迪肯大学 2023-07-14 CN claimed
EP-0411709-B1 Polyamide composition DSM NV (NL) 1994-06-01 EP claimed
EP-0270146-B1 COPOLYAMIDE AND A PROCESS FOR THE PREPARATION THEREOF DSM N.V. (NL) 1992-09-23 EP claimed
US-4849498-A WATERPROOF NYLON STAMICARBON B.V. (NL) 1989-07-18 US claimed
EP-0270146-A1 Copolyamide and a process for the preparation thereof DSM N.V. (NL) 1988-06-08 EP claimed
JP-3149224-A None JP disclosed
EP-3560987-B1 GLASS FIBER-REINFORCED RESIN MOLDED ARTICLE NITTO BOSEKI CO LTD (JP) 2023-09-13 EP disclosed
CN-115551951-A Thermally conductive resin composition and molded body made of same 尤尼吉可株式会社 2022-12-30 CN disclosed
US-11059946-B2 Glass fiber-reinforced resin molded article NITTO BOSEKI CO., LTD. (JP) 2021-07-13 US disclosed
CN-108292692-B Method for manufacturing optical semiconductor device, thermosetting resin composition for the same, and optical semiconductor obtained therefrom 衡所华威电子有限公司 2021-01-12 CN disclosed
US-10676616-B2 Polyamide resin composition TOYOBO CO., LTD. (JP) 2020-06-09 US disclosed
CN-110944682-A Scaffolds for cell culture and tissue regeneration 迪肯大学 2020-03-31 CN disclosed
EP-0926175-A2 Liquid-crystalline resin and thermoplastic resin composition containing the liquid-crystalline resin TORAY INDUSTRIES, INC. (JP) 1999-06-30 EP disclosed
US-5852108-A Composite particulate material for resin reinforcement, production thereof, and reinforced resin composition incorporated therewith TORAY INDUSTRIES, INC. (JP) 1998-12-22 US disclosed
EP-0270146-B1 COPOLYAMIDE AND A PROCESS FOR THE PREPARATION THEREOF DSM N.V. (NL) 1992-09-23 EP disclosed
JP-H03149224-A POLYAMIDE COMPOSITION AND MOLDING, FILM AND FIBER OBTAINED THEREFROM STAMICARBON BV 1991-06-25 JP disclosed
US-4849498-A WATERPROOF NYLON STAMICARBON B.V. (NL) 1989-07-18 US disclosed
US-4849498-A WATERPROOF NYLON STAMICARBON B.V. (NL) 1989-07-18 US disclosed
EP-0270146-A1 Copolyamide and a process for the preparation thereof DSM N.V. (NL) 1988-06-08 EP disclosed
EP-0270146-A1 Copolyamide and a process for the preparation thereof DSM N.V. (NL) 1988-06-08 EP disclosed