SCHEMBL918600

SCHEMBL918600

NC(=O)c1ccc2c(C(N)=O)c1CCCCCCCCC2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 7/20 0.41
ALDH1A1 P00352 7/20 0.41
MAPT P10636 6/20 0.41
ALOX15 P16050 6/20 0.41
KDM4E B2RXH2 5/20 0.41
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
MAPK1 P28482 4/20 0.41
HPGD P15428 4/20 0.41
CASP1 P29466 2/20 0.39
CASP7 P55210 2/20 0.39
USP2 O75604 2/20 0.39
NPC1 O15118 6/20 0.37
RAB9A P51151 5/20 0.37
LMNA P02545 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
MAPK8 P45983 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8864195 1.00 HSD17B10 (0.41) HSD17B10ALDH1A1MAPTALOX15KDM4E
SCHEMBL10942539 1.00 HSD17B10 (0.41) HSD17B10ALDH1A1MAPTALOX15KDM4E
SCHEMBL18489764 1.00 HSD17B10 (0.41) HSD17B10ALDH1A1MAPTALOX15KDM4E
SCHEMBL36051 1.00 HSD17B10 (0.41) HSD17B10ALDH1A1MAPTALOX15KDM4E
SCHEMBL6052857 0.98 HSD17B10 (0.40) HSD17B10ALDH1A1MAPTALOX15KDM4E
SCHEMBL472840 0.98 MAPT (0.40) HSD17B10ALDH1A1MAPTALOX15KDM4E
SCHEMBL6466252 0.87 PARP1 (0.37) HSD17B10ALDH1A1MAPTALOX15KDM4E
SCHEMBL6436615 0.86 HSD17B10 (0.41) HSD17B10ALDH1A1MAPTALOX15KDM4E
SCHEMBL4566904 0.86 HSD17B10 (0.41) HSD17B10ALDH1A1MAPTALOX15KDM4E
SCHEMBL3375681 0.83 ALOX15 (0.37) HSD17B10ALOX15MAPK1CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3135715-B1 FIBER-REINFORCED PLASTIC JOINED BODY, METHOD FOR PRODUCING FIBER-REINFORCED PLASTIC JOINED BODY, AND FIBER-REINFORCED MOLDED ARTICLE TEIJIN LTD (JP) 2020-07-29 EP disclosed
WO-2020137128-A1 LAMINATE 宇部興産株式会社 2020-07-02 WO disclosed
US-10155341-B2 Fiber-reinforced plastic joined body, method for producing fiber-reinforced plastic joined body, and fiber-reinforced molded article TEIJIN LIMITED (JP) 2018-12-18 US disclosed
EP-3135715-A1 FIBER-REINFORCED PLASTIC JOINED BODY, METHOD FOR PRODUCING FIBER-REINFORCED PLASTIC JOINED BODY, AND FIBER-REINFORCED MOLDED ARTICLE Teijin Limited (JP) 2017-03-01 EP disclosed
US-20170043526-A1 Fiber-Reinforced Plastic Joined Body, Method for Producing Fiber-Reinforced Plastic Joined Body, and Fiber-Reinforced Molded Article TEIJIN LIMITED (JP) 2017-02-16 US disclosed
US-20110003100-A1 POLYESTER COMPOSITION AND POLYESTER MOLDED ARTICLE COMPRISING THE SAME TOYO BOSEKI KABUSHIKI KAISHA (JP) 2011-01-06 US disclosed