Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL472840 | 0.89 | MAPT (0.40) | PARP1ALDH1A1HPGDKMT2AKDM4E | |
| Hexane SCHEMBL8160107 | 0.88 | MEN1 (0.40) | PARP1ALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL8864195 | 0.87 | HSD17B10 (0.41) | PARP1ALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL918600 | 0.87 | HSD17B10 (0.41) | PARP1ALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL36051 | 0.87 | HSD17B10 (0.41) | PARP1ALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL18489764 | 0.87 | HSD17B10 (0.41) | PARP1ALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL10942539 | 0.87 | HSD17B10 (0.41) | PARP1ALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL6052857 | 0.85 | HSD17B10 (0.40) | PARP1ALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL8362799 | 0.80 | MAPT (0.42) | PARP1ALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL3258685 | 0.74 | MAPT (0.40) | PARP1ALDH1A1HPGDKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104436-B1 | TOP FILM FOR SKIN PACKINGS | W.R. GRACE & CO. (US) | 1987-11-19 | — | — | EP | claimed |
| EP-1599540-A1 | THERMOPLASTIC ELASTOMER COMPOSITION WITH AN IMPROVED RUBBER PELLETIZATION PROCESS | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004081108-A1 | THERMOPLASTIC ELASTOMER COMPOSITION WITH AN IMPROVED RUBBER PELLETIZATION PROCESS | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2004-09-23 | — | — | WO | disclosed |