SCHEMBL36051

SCHEMBL36051

NC(=O)c1ccc2c(C(N)=O)c1CCCCCC2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 7/20 0.41
ALDH1A1 P00352 7/20 0.41
MAPT P10636 6/20 0.41
ALOX15 P16050 6/20 0.41
KDM4E B2RXH2 5/20 0.41
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
MAPK1 P28482 4/20 0.41
HPGD P15428 4/20 0.41
CASP1 P29466 2/20 0.39
CASP7 P55210 2/20 0.39
USP2 O75604 2/20 0.39
NPC1 O15118 6/20 0.37
RAB9A P51151 5/20 0.37
LMNA P02545 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
MAPK8 P45983 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8864195 1.00 HSD17B10 (0.41) HSD17B10ALDH1A1MAPTALOX15KDM4E
SCHEMBL918600 1.00 HSD17B10 (0.41) HSD17B10ALDH1A1MAPTALOX15KDM4E
SCHEMBL10942539 1.00 HSD17B10 (0.41) HSD17B10ALDH1A1MAPTALOX15KDM4E
SCHEMBL18489764 1.00 HSD17B10 (0.41) HSD17B10ALDH1A1MAPTALOX15KDM4E
SCHEMBL6052857 0.98 HSD17B10 (0.40) HSD17B10ALDH1A1MAPTALOX15KDM4E
SCHEMBL472840 0.98 MAPT (0.40) HSD17B10ALDH1A1MAPTALOX15KDM4E
SCHEMBL6466252 0.87 PARP1 (0.37) HSD17B10ALDH1A1MAPTALOX15KDM4E
SCHEMBL6436615 0.86 HSD17B10 (0.41) HSD17B10ALDH1A1MAPTALOX15KDM4E
SCHEMBL4566904 0.86 HSD17B10 (0.41) HSD17B10ALDH1A1MAPTALOX15KDM4E
SCHEMBL3375681 0.83 ALOX15 (0.37) HSD17B10ALOX15MAPK1CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240018356-A1 REINFORCED THERMOPLASTIC MOULDING COMPOSITION EMS-PATENT AG (CH) 2024-01-18 US claimed
EP-3884013-B1 DIRECT CONVERSION OF PLASTIC MATERIALS INTO METHANE AND/OR LIQUID FUELS ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) 2024-01-10 EP claimed
US-11814517-B2 Reinforced thermoplastic moulding composition EMS-PATENT AG (CH) 2023-11-14 US claimed
CN-114085492-A Resin composition, prepreg and laminated board thereof 苏州生益科技有限公司 2022-02-25 CN claimed
US-11041047-B2 Conductive thermoplastic polyamide molding compound EMS-PATENT AG (CH) 2021-06-22 US claimed
EP-3484957-B1 CONDUCTIVE THERMOPLASTIC POLYAMIDE MOULDING MATERIAL EMS CHEMIE AG (CH) 2021-05-26 EP claimed
EP-3725833-B1 REINFORCED THERMPOLASTISCHE MOULDING COMPOSITION EMS CHEMIE AG (CH) 2021-03-17 EP claimed
US-20200332118-A1 REINFORCED THERMOPLASTIC MOULDING COMPOSITION EMS-PATENT AG (CH) 2020-10-22 US claimed
US-20190225750-A1 CONDUCTIVE THERMOPLASTIC POLYAMIDE MOULDING COMPOUND EMS-PATENT AG (CH) 2019-07-25 US claimed
EP-2438113-B1 FLAME-PROTECTED, PARTIALLY AROMATIC POLYAMIDE MOLDING COMPOUNDS EMS PATENT AG (CH) 2019-07-24 EP claimed
EP-0358038-A1 Amorphous nylon copolymer and copolyamide films and blends VISKASE CORPORATION (US) 1990-03-14 EP claimed
EP-0128775-B1 RESINOUS COMPOSITION TORAY INDUSTRIES, INC. (JP) 1989-11-15 EP claimed
EP-0165022-B1 SELF-CRIMPING POLYAMIDE FILAMENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-10-18 EP claimed
EP-0291833-A1 Stabilised polyamide mouldings reinforced with glass fibres BAYER AG (DE) 1988-11-23 EP claimed
EP-0282730-A1 Glass fibre-reinforced polyamide moulding compositions with an increased salt and weather resistance BAYER AG (DE) 1988-09-21 EP claimed
EP-0262796-A2 Resin compositons and their manufacturing method TORAY INDUSTRIES, INC. (JP) 1988-04-06 EP claimed
EP-0104436-B1 TOP FILM FOR SKIN PACKINGS W.R. GRACE & CO. (US) 1987-11-19 EP claimed
US-4612346-A BLEND OF POLYAMIDE AND MODIFIED POLYOLEFIN TORAY INDUSTRIES, INC. (JP) 1986-09-16 US claimed
EP-0128775-A2 Resinous composition TORAY INDUSTRIES, INC. (JP) 1984-12-19 EP claimed
EP-0010938-B1 PROCESS AND COMPOSITIONS FOR PREPARING IMPACT-RESISTANT POLYAMIDE RESINS, AND ARTICLES MADE FROM SUCH RESINS MONSANTO COMPANY (US) 1983-03-16 EP claimed