Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.35 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | STK17B | O94768 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727314 | 0.88 | LMNA (0.40) | MAPTLMNAMEN1CYP1A2CYP2C9 | |
| SCHEMBL4726624 | 0.86 | ALDH1A1 (0.34) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL4728256 | 0.86 | ALPG (0.41) | MAPTLMNAKMT2AKDM4ETDP1 | |
| SCHEMBL4726886 | 0.86 | TDP2 (0.41) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL4784487 | 0.85 | ALDH1A1 (0.40) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL4730667 | 0.84 | CNR2 (0.37) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL2171555 | 0.83 | ALDH1A1 (0.45) | MAPTMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4728535 | 0.81 | CYP11B2 (0.40) | MAPTLMNAMEN1CYP1A2CYP2C9 | |
| SCHEMBL4730195 | 0.79 | ALPG (0.41) | MAPTLMNAKMT2AKDM4ETDP1 | |
| SCHEMBL4726120 | 0.79 | TDP2 (0.39) | MAPTLMNAMEN1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |