Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 8/20 | 0.49 |
| ▸ | P4HB | P07237 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | IL6 | P05231 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5644762 | 1.00 | NFKB1 (0.53) | NFKB1MAOBP4HBABCG2GRIN2D | |
| SCHEMBL9683791 | 0.84 | NFKB1 (0.38) | NFKB1MAOBP4HBABCG2GRIN2D | |
| SCHEMBL9681814 | 0.82 | NFKB1 (0.37) | NFKB1MAOBLMNA | |
| SCHEMBL9514028 | 0.82 | NFKB1 (0.37) | NFKB1MAOBLMNA | |
| SCHEMBL2396436 | 0.81 | NFKB1 (0.58) | NFKB1MAOBP4HBABCG2GRIN2D | |
| SCHEMBL4281994 | 0.81 | NFKB1 (0.58) | NFKB1MAOBP4HBABCG2GRIN2D | |
| SCHEMBL9682815 | 0.80 | NOTUM (0.37) | NFKB1MAOBLMNA | |
| SCHEMBL10383610 | 0.79 | KDM4E (0.40) | LMNAMEN1KMT2A | |
| SCHEMBL19052385 | 0.78 | NFKB1 (0.50) | NFKB1MAOBP4HBABCG2GRIN2D | |
| SCHEMBL7016426 | 0.77 | APP (0.39) | MAOBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035381-A2 | PROCESS FOR THE PREPARATION OF AMINE DERIVATIVES AS CALCIMIMETICS | IND-SWIFT LABORATORIES LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |