Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 4/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9514028 | 1.00 | NFKB1 (0.37) | NFKB1LMNAKDM4EARMAOB | |
| SCHEMBL9682815 | 0.86 | NOTUM (0.37) | NFKB1LMNAARMAOBSMN1; SMN2 | |
| SCHEMBL5644762 | 0.82 | NFKB1 (0.53) | NFKB1LMNAMAOB | |
| SCHEMBL4728560 | 0.82 | NFKB1 (0.53) | NFKB1LMNAMAOB | |
| SCHEMBL9683791 | 0.81 | NFKB1 (0.38) | NFKB1LMNAARMAOBSMN1; SMN2 | |
| SCHEMBL8230502 | 0.79 | NFKB1 (0.41) | NFKB1LMNAKDM4EMAOBTAS2R14 | |
| SCHEMBL11278545 | 0.77 | KDM4E (0.36) | NFKB1KDM4ESMN1; SMN2ENPP2 | |
| SCHEMBL11278542 | 0.77 | KDM4E (0.36) | NFKB1KDM4ESMN1; SMN2ENPP2 | |
| SCHEMBL11072708 | 0.73 | NFKB1 (0.38) | NFKB1KDM4EMAOBTAS2R14CTSS | |
| SCHEMBL735425 | 0.73 | ALDH1A1 (0.43) | NFKB1LMNAKDM4ETAS2R14CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166395-A | Chemical intermediates with trifluoromethyl derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1992-11-24 | — | — | US | disclosed |
| US-5091408-A | FUNGICIDAL 3-CYANO-4-PHENYL-PYRROLES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |