Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | P4HB | P07237 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | IL6 | P05231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728560 | 0.84 | NFKB1 (0.53) | NFKB1MAOBLMNAP4HBABCG2 | |
| SCHEMBL5644762 | 0.84 | NFKB1 (0.53) | NFKB1MAOBLMNAP4HBABCG2 | |
| SCHEMBL9681814 | 0.81 | NFKB1 (0.37) | NFKB1MAOBLMNASMN1; SMN2ENPP2 | |
| SCHEMBL9514028 | 0.81 | NFKB1 (0.37) | NFKB1MAOBLMNASMN1; SMN2ENPP2 | |
| SCHEMBL9682815 | 0.75 | NOTUM (0.37) | NFKB1MAOBLMNASMN1; SMN2HSD11B1 | |
| SCHEMBL2030928 | 0.72 | NFE2L2 (0.35) | NFKB1HSD11B1ENPP2AR | |
| SCHEMBL2030929 | 0.72 | NFE2L2 (0.35) | NFKB1HSD11B1ENPP2AR | |
| SCHEMBL1600817 | 0.72 | PIM1 (0.43) | NFKB1MAOBLMNAHSD11B1P4HB | |
| SCHEMBL453534 | 0.72 | NFKB1 (0.39) | NFKB1MAOBLMNAHSD11B1P4HB | |
| SCHEMBL6391430 | 0.70 | NFKB1 (0.54) | NFKB1MAOBLMNASMN1; SMN2P4HB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166395-A | Chemical intermediates with trifluoromethyl derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1992-11-24 | — | — | US | disclosed |
| US-5091408-A | FUNGICIDAL 3-CYANO-4-PHENYL-PYRROLES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |