Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9514028 | 0.86 | NFKB1 (0.37) | NOTUMARNFKB1LMNAMAOB | |
| SCHEMBL9681814 | 0.86 | NFKB1 (0.37) | NOTUMARNFKB1LMNAMAOB | |
| SCHEMBL5644762 | 0.80 | NFKB1 (0.53) | NFKB1LMNAMAOB | |
| SCHEMBL4728560 | 0.80 | NFKB1 (0.53) | NFKB1LMNAMAOB | |
| SCHEMBL9683791 | 0.75 | NFKB1 (0.38) | ARHSD11B1NFKB1LMNAMAOB | |
| SCHEMBL26375361 | 0.70 | HSD11B1 (0.50) | NOTUMHSD11B1TAS2R14PDCD1CD274 | |
| SCHEMBL7931796 | 0.69 | HPGD (0.38) | NFKB1SMN1; SMN2 | |
| SCHEMBL7931798 | 0.69 | HPGD (0.38) | NFKB1SMN1; SMN2 | |
| SCHEMBL11125534 | 0.69 | ESR2 (0.37) | — | |
| SCHEMBL10383610 | 0.68 | KDM4E (0.40) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166395-A | Chemical intermediates with trifluoromethyl derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1992-11-24 | — | — | US | claimed |