Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.41 |
| ▸ | PRKAB2 | O43741 | 5/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 5/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 5/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 5/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 5/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 5/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 5/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728060 | 0.89 | ALPL (0.43) | ALPLKDM4EALDH1A1HSD17B10HCAR2 | |
| SCHEMBL4729634 | 0.85 | KDM4E (0.40) | KDM4EALDH1A1HSD17B10GLAPOLB | |
| SCHEMBL4727175 | 0.83 | HCAR2 (0.39) | ALPLKDM4EALDH1A1HSD17B10HCAR2 | |
| SCHEMBL4730399 | 0.81 | ALPL (0.40) | ALPLKDM4EALDH1A1HSD17B10HCAR2 | |
| SCHEMBL4779778 | 0.81 | ALPL (0.40) | ALPLKDM4EALDH1A1HSD17B10HCAR2 | |
| SCHEMBL2171482 | 0.81 | KDM4E (0.59) | ALPLKDM4EALDH1A1HSD17B10HCAR2 | |
| SCHEMBL4727651 | 0.80 | MARS1 (0.43) | ALPLPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL4730236 | 0.80 | ESRRB (0.39) | ALPLKDM4EALDH1A1HSD17B10PRKAB2 | |
| SCHEMBL2171831 | 0.79 | HCAR2 (0.40) | ALPLKDM4EALDH1A1HSD17B10HCAR2 | |
| SCHEMBL4726990 | 0.79 | PDGFRB (0.40) | ALPLALDH1A1PRKAB2PRKAG1PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |