Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRB | O95718 | 1/20 | 0.39 |
| ▸ | ESRRA | P11474 | 1/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 5/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 5/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 5/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 5/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 5/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 5/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 5/20 | 0.39 |
| ▸ | ALPL | P05186 | 2/20 | 0.37 |
| ▸ | MARS1 | P56192 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727651 | 0.91 | MARS1 (0.43) | ESRRBESRRAPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL4728060 | 0.88 | ALPL (0.43) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL4726979 | 0.87 | SMN1; SMN2 (0.39) | ALPLMAPK1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL4730399 | 0.84 | ALPL (0.40) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL4779778 | 0.84 | ALPL (0.40) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL4729857 | 0.84 | PRKAB2 (0.47) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL4726990 | 0.82 | PDGFRB (0.40) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL4728706 | 0.80 | ALPL (0.43) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL4728276 | 0.78 | MAPT (0.43) | ALPLMAPK1CNR1CNR2KCNH2 | |
| SCHEMBL4731322 | 0.77 | MARS1 (0.44) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |