Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.69 |
| ▸ | HTR1A | P08908 | 9/20 | 0.69 |
| ▸ | HTR2A | P28223 | 9/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.69 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725569 | 0.95 | HTR1A (0.62) | DRD2HTR1AHTR2AKCNH2HRH3 | |
| SCHEMBL4729828 | 0.82 | HTR1A (0.72) | DRD2HTR1AHTR2AKCNH2 | |
| SCHEMBL4726781 | 0.82 | HTR1A (0.62) | DRD2HTR1AHTR2AKCNH2 | |
| SCHEMBL4725686 | 0.82 | DRD2 (1.00) | DRD2HTR1AHTR2AKCNH2 | |
| SCHEMBL4725843 | 0.79 | DRD2 (1.00) | DRD2HTR1AHTR2AKCNH2 | |
| SCHEMBL4726778 | 0.78 | HTR2A (0.49) | DRD2HTR1AHTR2AKCNH2HRH3 | |
| SCHEMBL4729824 | 0.78 | DRD2 (0.51) | DRD2HTR1AHTR2AKCNH2HRH3 | |
| SCHEMBL4728930 | 0.77 | DRD2 (0.91) | DRD2HTR1AHTR2AKCNH2 | |
| SCHEMBL9018059 | 0.75 | HTR2A (0.56) | DRD2HTR1AHTR2AKCNH2MAPT | |
| SCHEMBL4729511 | 0.74 | DRD2 (1.00) | DRD2HTR1AHTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008020306-A2 | ISOINDOLE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2008-02-21 | — | — | WO | claimed |