Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.35 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733183 | 0.91 | SMN1; SMN2 (0.36) | KCNK2CHRM3MEN1LMNAPLA2G1B | |
| SCHEMBL4733534 | 0.90 | AKR1C3 (0.35) | CHRM3ALDH1A1MEN1LMNAPLA2G1B | |
| SCHEMBL4730702 | 0.88 | MAPT (0.41) | RXFP1HDAC4MEF2DTRPV1KCNK2 | |
| SCHEMBL1018834 | 0.82 | CHRM3 (0.44) | CHRM3ALDH1A1MEN1KMT2ATACR1 | |
| SCHEMBL4731393 | 0.81 | CA2 (0.39) | MEN1KMT2A | |
| SCHEMBL1019446 | 0.80 | POLB (0.38) | CHRM3ALDH1A1MEN1LMNAPLA2G1B | |
| SCHEMBL1024112 | 0.80 | CHRM3 (0.40) | CHRM3MEN1KMT2A | |
| SCHEMBL4733535 | 0.79 | MAPT (0.41) | CHRM3ALDH1A1MEN1LMNAPLA2G1B | |
| SCHEMBL4794346 | 0.79 | RXFP1 (0.37) | RXFP1CHRM3ALDH1A1LMNA | |
| SCHEMBL4734232 | 0.78 | MAPT (0.41) | KCNK2CHRM3ALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008053044-A2 | HETARYL CARBON ACID-N-(BIPHEN-2-YL)AMIDE COMPOUNDS | BASF SE (DE) | 2008-05-08 | — | — | WO | claimed |
| WO-2008053044-A2 | HETARYL CARBON ACID-N-(BIPHEN-2-YL)AMIDE COMPOUNDS | BASF SE (DE) | 2008-05-08 | — | — | WO | disclosed |