Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.35 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 5/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729048 | 0.91 | RXFP1 (0.35) | LMNAL3MBTL1MEN1KMT2AKCNK2 | |
| SCHEMBL1018834 | 0.87 | CHRM3 (0.44) | MEN1KMT2ANPC1RAB9ACHRM3 | |
| SCHEMBL4734232 | 0.87 | MAPT (0.41) | SMN1; SMN2LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL1019446 | 0.85 | POLB (0.38) | LMNAL3MBTL1MEN1KMT2APLA2G1B | |
| SCHEMBL4733778 | 0.83 | ALDH1A1 (0.38) | SMN1; SMN2L3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL4733534 | 0.82 | AKR1C3 (0.35) | SMN1; SMN2LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL4733467 | 0.82 | CA2 (0.44) | MEN1KMT2APOLBMAPT | |
| SCHEMBL4732011 | 0.81 | ALDH1A1 (0.37) | SMN1; SMN2LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL1024112 | 0.79 | CHRM3 (0.40) | MEN1KMT2ANPSR1NPC1RAB9A | |
| SCHEMBL1128032 | 0.79 | CHRM3 (0.36) | SMN1; SMN2LMNAL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008053044-A2 | HETARYL CARBON ACID-N-(BIPHEN-2-YL)AMIDE COMPOUNDS | BASF SE (DE) | 2008-05-08 | — | — | WO | claimed |
| WO-2008053044-A2 | HETARYL CARBON ACID-N-(BIPHEN-2-YL)AMIDE COMPOUNDS | BASF SE (DE) | 2008-05-08 | — | — | WO | disclosed |