Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733366 | 0.85 | MALT1 (0.46) | MALT1MEN1KMT2ACNR1CNR2 | |
| SCHEMBL5096292 | 0.85 | ALDH1A1 (0.47) | MEN1KMT2ACNR1CNR2LMNA | |
| SCHEMBL4728680 | 0.81 | GRM4 (0.46) | MALT1MEN1KMT2AMAPK1DRD2 | |
| SCHEMBL4731982 | 0.81 | SCD (0.50) | MALT1MEN1KMT2ALMNAHTT | |
| SCHEMBL4732425 | 0.81 | FPR2 (0.49) | MEN1KMT2ACNR1CNR2LMNA | |
| SCHEMBL5102669 | 0.79 | MALT1 (0.46) | MALT1MEN1KMT2ACNR1CNR2 | |
| SCHEMBL4729025 | 0.78 | MALT1 (0.50) | MALT1MEN1KMT2ACNR1CNR2 | |
| SCHEMBL4731971 | 0.77 | MEN1 (0.47) | MALT1MEN1KMT2ACNR1CNR2 | |
| SCHEMBL14175664 | 0.75 | SLC6A7 (0.58) | MALT1MEN1KMT2ACNR1CNR2 | |
| SCHEMBL4729599 | 0.75 | KMT2A (0.43) | MEN1KMT2ACNR1CNR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008058064-A1 | AMINE-LINKED MULTICYCLIC COMPOUNDS AS INHIBITORS OF THE PROLINE TRANSPORTER | LEXICON PHARMACEUTICALS, INC. (US) | 2008-05-15 | — | — | WO | disclosed |