SCHEMBL472983

SCHEMBL472983

Nc1ccccc1C(=O)Nc1cccc(Cl)c1

nearest known ligand 0.78

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FADS1 O60427 6/20 0.78
PTGS1 P23219 1/20 0.63
NPC1 O15118 3/20 0.62
RAB9A P51151 3/20 0.62
ALDH1A1 P00352 2/20 0.62
KDM4E B2RXH2 2/20 0.62
GRM4 Q14833 2/20 0.62
P2RX1 P51575 1/20 0.61
P2RX4 Q99571 1/20 0.61
P2RX7 Q99572 1/20 0.61
HDAC6 Q9UBN7 1/20 0.57
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
LMNA P02545 2/20 0.57
MAPT P10636 2/20 0.57
HTT P42858 2/20 0.57
GRM5 P41594 2/20 0.57
GAA P10253 1/20 0.56
MAOB P27338 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29406000 1.00 FADS1 (0.78) FADS1PTGS1NPC1RAB9AALDH1A1
SCHEMBL17744881 0.89 FADS1 (0.72) FADS1PTGS1NPC1RAB9AALDH1A1
SCHEMBL9810110 0.84 ALDH1A1 (0.72) FADS1PTGS1NPC1RAB9AALDH1A1
SCHEMBL15778718 0.84 FADS1 (0.74) FADS1NPC1RAB9AALDH1A1GRM4
SCHEMBL4738811 0.84 FADS1 (0.72) FADS1NPC1RAB9AALDH1A1KDM4E
SCHEMBL2701738 0.83 FADS1 (1.00) FADS1NPC1RAB9AALDH1A1KDM4E
SCHEMBL31424193 0.83 MEN1 (0.72) FADS1PTGS1NPC1RAB9AALDH1A1
SCHEMBL5668126 0.83 FADS1 (0.65) FADS1PTGS1NPC1RAB9AALDH1A1
SCHEMBL259352 0.83 MEN1 (0.72) FADS1PTGS1NPC1RAB9AALDH1A1
SCHEMBL8485797 0.83 FADS1 (0.65) FADS1PTGS1NPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105814209-B Microbial oils containing dihomo-gamma-linolenic acid and microbial biomass containing dihomo-gamma-linolenic acid 日本水产株式会社 2022-02-25 CN claimed
CN-112980897-A Preparation method of microbial oil containing dihomo-gamma-linolenic acid 日本水产株式会社 2021-06-18 CN claimed
EP-3733857-A2 DIHOMO-GAMMA-LINOLENIC ACID-CONTAINING MICROBIAL OIL AND DIHOMO-GAMMA-LINOLENIC ACID-CONTAINING MICROBIAL BIOMASS Nippon Suisan Kaisha, Ltd. (JP) 2020-11-04 EP claimed
EP-3563690-A2 DIHOMO-GAMMA-LINOLENIC ACID-CONTAINING MICROBIAL OIL AND DIHOMO-GAMMA-LINOLENIC ACID-CONTAINING MICROBIAL BIOMASS Nippon Suisan Kaisha, Ltd. (JP) 2019-11-06 EP claimed
US-20180042230-A1 DIHOMO-GAMMA-LINOLENIC ACID-CONTAINING MICROBIAL OIL AND DIHOMO-GAMMA-LINOLENIC ACID-CONTAINING MICROBIAL BIOMASS NIPPON SUISAN KAISHA, LTD. (JP) 2018-02-15 US claimed
US-20170000116-A1 DIHOMO-GAMMA-LINOLENIC ACID-CONTAINING MICROBIAL OIL AND DIHOMO-GAMMA-LINOLENIC ACID-CONTAINING MICROBIAL BIOMASS NIPPON SUISAN KAISHA, LTD. (JP) 2017-01-05 US claimed
EP-3077489-A2 DIHOMO- -LINOLENIC ACID-CONTAINING MICROBIAL OIL AND DIHOMO- -LINOLENIC ACID-CONTAINING MICROBIAL BIOMASS Nippon Suisan Kaisha, Ltd. (JP) 2016-10-12 EP claimed
WO-2015083843-A2 DIHOMO-γ-LINOLENIC ACID-CONTAINING MICROBIAL OIL AND DIHOMO-γ-LINOLENIC ACID-CONTAINING MICROBIAL BIOMASS NIPPON SUISAN KAISHA, LTD. (JP) 2015-06-11 WO claimed
CN-104193898-A Salt-free high-temperature-resistant powder butadiene-acrylonitrile rubber SHENGDONG TECHNOLOGY CO LTD 2014-12-10 CN claimed
CN-104193907-A High-temperature resistant powdered acrylonitrile-butadiene rubber SHENGDONG TECHNOLOGY CO LTD 2014-12-10 CN claimed
CN-117510415-A Synthesis method of quinazolinone compound 中国人民解放军军事科学院防化研究院 2024-02-06 CN disclosed
US-11856952-B2 Microbial oil, production method for microbial oil, concentrated microbial oil, and production method for concentrated microbial oil NIPPON SUISAN KAISHA, LTD. (JP) 2024-01-02 US disclosed
CN-111646908-B Method for preparing aromatic amine compound 宜昌尚诺德生物医药科技有限公司 2023-03-10 CN disclosed
CN-111732493-B Synthesis process of arylamine compound 宜昌尚诺德生物医药科技有限公司 2023-01-24 CN disclosed
US-20220248671-A1 MICROBIAL OIL, PRODUCTION METHOD FOR MICROBIAL OIL, CONCENTRATED MICROBIAL OIL, AND PRODUCTION METHOD FOR CONCENTRATED MICROBIAL OIL NIPPON SUISAN KAISHA, LTD. (JP) 2022-08-11 US disclosed
US-20020019414-A1 N-aryl(thio)anthranilic acid amide derivatives, their preparation and their use as VEGF receptor tyrosine kinase inhibitors NOVARTIS AG (CH) 2002-02-14 US disclosed
CN-1331680-A N-aryl (thio) anthranilic acid amide derivatives, their prepn. and their use as VEGF receptor tyrosine kinase inhibitors NOVARTIS AG (CH) 2002-01-16 CN disclosed
US-6313122-B1 AS INHIBITORS OF FACTOR XA AND ARE USED AS ANTICOAGULANTS IN MAMMALS ELI LILLY AND COMPANY 2001-11-06 US disclosed
EP-1014962-A1 ANTITHROMBOTIC AGENTS ELI LILLY AND COMPANY (US) 2000-07-05 EP disclosed
WO-1999000121-A1 ANTITHROMBOTIC AGENTS ELI LILLY AND COMPANY (US) 1999-01-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170000116-A1 DIHOMO-GAMMA-LINOLENIC ACID-CONTAINING MICROBIAL OIL AND DIHOMO-GAMMA-LINOLENIC ACID-CONTAINING MICROBIAL BIOMASS DAGLA, DAGLB, DGKA FADS1 34/4885PTGS1 257/4885NPC1 2694/4885
US-20020019414-A1 N-aryl(thio)anthranilic acid amide derivatives, their preparation and their use as VEGF receptor tyrosine kinase inhibitors AXL, TYRO3, KDR FADS1 3125/4885PTGS1 826/4885NPC1 4229/4885
US-20180042230-A1 DIHOMO-GAMMA-LINOLENIC ACID-CONTAINING MICROBIAL OIL AND DIHOMO-GAMMA-LINOLENIC ACID-CONTAINING MICROBIAL BIOMASS DAGLA, DAGLB, DGKA FADS1 34/4885PTGS1 257/4885NPC1 2694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.