Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.39 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731778 | 0.91 | GAA (0.46) | RAB9AKMT2ANAMPTABL1CNR2 | |
| SCHEMBL4730642 | 0.83 | ALDH1A1 (0.47) | RAB9AKMT2AABL1CNR2ALDH1A1 | |
| SCHEMBL4734236 | 0.78 | CNR2 (0.41) | RAB9AKMT2ANAMPTCNR2CNR1 | |
| SCHEMBL4729966 | 0.74 | CNR2 (0.41) | RAB9AKMT2ANAMPTCNR2CNR1 | |
| SCHEMBL4729959 | 0.72 | CNR2 (0.51) | RAB9AABL1CNR2CNR1 | |
| SCHEMBL4730027 | 0.68 | CNR2 (0.42) | RAB9AKMT2ANAMPTCNR2CNR1 | |
| SCHEMBL4729137 | 0.66 | CNR2 (0.80) | CNR2CNR1 | |
| SCHEMBL14206664 | 0.66 | CNR2 (0.58) | KMT2ACNR2CNR1ALDH1A1MEN1 | |
| SCHEMBL14207395 | 0.66 | CNR2 (0.60) | RAB9AABL1CNR2CNR1ALDH1A1 | |
| SCHEMBL27753617 | 0.65 | NPY5R (0.53) | RAB9ACNR2CNR1ALDH1A1NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | claimed |
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |