Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | HPGD | P15428 | 2/20 | 0.73 |
| ▸ | MLNR | O43193 | 1/20 | 0.73 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.73 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.73 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.73 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.73 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.73 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.73 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.73 |
| ▸ | PDE4A | P27815 | 1/20 | 0.73 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729232 | 0.85 | POLB (0.63) | CYP1A2CYP3A4MAPK1HSD17B10CYP2D6 | |
| Glafenine SCHEMBL29438081 | 0.85 | CYP1A2 (1.00) | CYP1A2CYP3A4MAPK1HSD17B10CYP2D6 | |
| Glafenine SCHEMBL24246 | 0.85 | CYP1A2 (1.00) | CYP1A2CYP3A4MAPK1HSD17B10CYP2D6 | |
| SCHEMBL4734517 | 0.84 | POLB (0.60) | CYP1A2CYP3A4MAPK1HSD17B10CYP2D6 | |
| Glafenine SCHEMBL970807 | 0.84 | CYP1A2 (0.98) | CYP1A2CYP3A4MAPK1HSD17B10CYP2D6 | |
| SCHEMBL4732484 | 0.82 | POLB (0.56) | CYP1A2CYP3A4MAPK1HSD17B10CYP2D6 | |
| Hydrochloric Acid SCHEMBL4732480 | 0.81 | POLB (0.55) | CYP1A2CYP3A4MAPK1HSD17B10CYP2D6 | |
| SCHEMBL4729504 | 0.81 | CXCL8 (0.62) | CYP1A2CYP3A4MAPK1HSD17B10CYP2D6 | |
| Hydrochloric Acid SCHEMBL4733095 | 0.80 | CYP2C9 (0.60) | CYP1A2CYP3A4MAPK1HSD17B10CYP2D6 | |
| SCHEMBL4748775 | 0.78 | POLB (0.62) | CYP1A2CYP3A4MAPK1HSD17B10CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139611-A1 | METHODS OF USING 4-PHENYLAMINOQUINOLINES AS TOPICAL NON-STEROIDAL ANTIINFLAMMATORY COMPOUNDS | MILESTONE PHARMACEUTICALS, INC. (CA) | 2008-06-12 | — | — | US | disclosed |
| WO-2008048577-A1 | METHODS OF USING 4-PHENYLAMINOQUINOLINES AS TOPICAL NON-STEROIDAL ANTIINFLAMMATORY COMPOUNDS | MILESTONE PHARMACEUTICALS INC. (CA) | 2008-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139611-A1 | METHODS OF USING 4-PHENYLAMINOQUINOLINES AS TOPICAL NON-STEROIDAL ANTIINFLAMMATORY COMPOUNDS | PTGES2, NFKBIA, PTGES | CYP1A2 236/4885CYP3A4 257/4885MAPK1 2723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.