Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.52 |
| ▸ | MLNR | O43193 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4732480 | 0.99 | POLB (0.55) | POLBTHRBCYP1A2CYP2D6KCNH2 | |
| SCHEMBL4729232 | 0.90 | POLB (0.63) | POLBTHRBCYP1A2CYP2D6KCNH2 | |
| SCHEMBL4734517 | 0.87 | POLB (0.60) | POLBTHRBCYP1A2CYP2D6KCNH2 | |
| SCHEMBL4730108 | 0.82 | CYP1A2 (0.73) | POLBTHRBCYP1A2CYP2D6KCNH2 | |
| SCHEMBL4729504 | 0.81 | CXCL8 (0.62) | POLBTHRBCYP1A2CYP2D6KCNH2 | |
| Hydrochloric Acid SCHEMBL4733095 | 0.80 | CYP2C9 (0.60) | POLBTHRBCYP1A2CYP2D6KCNH2 | |
| SCHEMBL4748775 | 0.77 | POLB (0.62) | POLBTHRBCYP1A2CYP2D6KCNH2 | |
| SCHEMBL21346888 | 0.76 | KDM4E (0.73) | POLBTHRBCYP1A2CYP2D6KCNH2 | |
| SCHEMBL11522711 | 0.76 | HSD17B10 (0.67) | POLBTHRBCYP1A2CYP2D6KCNH2 | |
| SCHEMBL13109329 | 0.74 | TTR (0.68) | CYP3A4CYP2C9MAPK1ABCB11PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139611-A1 | METHODS OF USING 4-PHENYLAMINOQUINOLINES AS TOPICAL NON-STEROIDAL ANTIINFLAMMATORY COMPOUNDS | MILESTONE PHARMACEUTICALS, INC. (CA) | 2008-06-12 | — | — | US | disclosed |
| WO-2008048577-A1 | METHODS OF USING 4-PHENYLAMINOQUINOLINES AS TOPICAL NON-STEROIDAL ANTIINFLAMMATORY COMPOUNDS | MILESTONE PHARMACEUTICALS INC. (CA) | 2008-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139611-A1 | METHODS OF USING 4-PHENYLAMINOQUINOLINES AS TOPICAL NON-STEROIDAL ANTIINFLAMMATORY COMPOUNDS | PTGES2, NFKBIA, PTGES | POLB 2390/4885THRB 4430/4885CYP1A2 236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.