SCHEMBL4730449

SCHEMBL4730449

[CH2]c1occc1P(=O)(O)O

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
POLB P06746 1/20 0.32
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
CA5A P35218 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4730454 0.73 LMNA (0.43) KDM4EPOLB
SCHEMBL4729288 0.68 CA2 (0.31) CA2CA4CA5A
SCHEMBL4134720 0.64
SCHEMBL27484131 0.62 CES2 (0.41) POLBCA2CA4CA5A
SCHEMBL3854285 0.62 CA2 (0.44) KDM4EPOLBCA2CA4CA5A
Ammonia Solution, Strong SCHEMBL27483808 0.62 CES2 (0.41) POLBCA2CA4CA5A
SCHEMBL27467975 0.62 CES2 (0.41) POLBCA2CA4CA5A
SCHEMBL27548546 0.62 CES2 (0.41) POLBCA2CA4CA5A
SCHEMBL2173729 0.61 CA2 (0.55) KDM4EPOLBCA2CA4CA5A
SCHEMBL29733396 0.61 CA2 (0.55) KDM4EPOLBCA2CA4CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008031888-A2 CONDENSED PYRIMIDINONES ACTIVE ON GLUTAMATERGIC RECEPTORS CAMPIANI GIUSEPPE (IT) 2008-03-20 WO claimed
WO-2008031888-A2 CONDENSED PYRIMIDINONES ACTIVE ON GLUTAMATERGIC RECEPTORS CAMPIANI GIUSEPPE (IT) 2008-03-20 WO disclosed