Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733076 | 0.84 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AKDM4ETAS1R3 | |
| SCHEMBL14203260 | 0.83 | KMT2A (0.48) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL9729410 | 0.81 | KMT2A (0.76) | ALDH1A1MEN1KMT2AKDM4ETUBB4A | |
| SCHEMBL9720532 | 0.81 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AKDM4ETAS1R3 | |
| SCHEMBL14204869 | 0.80 | THRA (0.57) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL12417592 | 0.79 | ALDH1A1 (0.86) | ALDH1A1MEN1KMT2AKDM4ETUBB4A | |
| SCHEMBL13886370 | 0.79 | MEN1 (0.49) | ALDH1A1MEN1KMT2AKDM4ETAS1R3 | |
| SCHEMBL9861846 | 0.78 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL10604070 | 0.78 | THRA (0.50) | ALDH1A1MEN1KMT2AKDM4ETAS1R3 | |
| SCHEMBL1021602 | 0.78 | MAPT (0.56) | ALDH1A1MEN1KMT2ATAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008052288-A1 | DITHIOLE COMPOUNDS AS COX INHIBITORS | NEURO THERAPEUTICS LIMITED (AU) | 2008-05-08 | — | — | WO | disclosed |
| WO-2008052288-A1 | DITHIOLE COMPOUNDS AS COX INHIBITORS | NEURO THERAPEUTICS LIMITED (AU) | 2008-05-08 | — | — | WO | disclosed |