Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | PPARA | Q07869 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720564 | 0.88 | ALDH1A1 (0.50) | ALDH1A1PPARAMEN1KMT2AKDM4E | |
| SCHEMBL16502263 | 0.85 | ALDH1A1 (0.46) | ALDH1A1PPARAMEN1KMT2AKDM4E | |
| SCHEMBL10604070 | 0.85 | THRA (0.50) | ALDH1A1PPARAMEN1KMT2AKDM4E | |
| SCHEMBL27916624 | 0.81 | PPARA (0.51) | ALDH1A1PPARAMEN1KMT2AKDM4E | |
| SCHEMBL6808598 | 0.81 | PPARA (0.50) | ALDH1A1PPARAMEN1KMT2AKDM4E | |
| SCHEMBL4730730 | 0.81 | ALDH1A1 (0.57) | ALDH1A1PPARAMEN1KMT2AKDM4E | |
| SCHEMBL9861846 | 0.81 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL10605850 | 0.80 | THRA (0.57) | ALDH1A1MEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL27916625 | 0.80 | THRA (0.50) | ALDH1A1PPARAMEN1KMT2AKDM4E | |
| SCHEMBL10603556 | 0.80 | PPARA (0.47) | ALDH1A1PPARAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5103022-A | Reacting dl-2-methyl-1-(4-trifluoromethylphenyl)-3-pyrrolidino -1-propanone with l-acetylphenylglycine to form corresponding diastereomeric salt, deposition, isolation of l-2-methyl-1-(4-trifluoromethylphenyl)-3-pyrrolidino-1-propanone | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1992-04-07 | — | — | US | disclosed |
| US-5057535-A | Muscle relaxants | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1991-10-15 | — | — | US | disclosed |
| EP-0173279-B1 | 2-(3,5-DIALKYL-4-HYDROXYPHENYL)INDOLE DERIVATIVES | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1989-08-23 | — | — | EP | disclosed |
| US-4695581-A | LIPOXYGENASE INHIBITOR | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1987-09-22 | — | — | US | disclosed |
| EP-0200942-A2 | New derivatives of an aminoketone | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1986-11-12 | — | — | EP | disclosed |
| EP-0173279-A1 | 2-(3,5-Dialkyl-4-hydroxyphenyl)indole derivatives | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1986-03-05 | — | — | EP | disclosed |