Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | BPTF | Q12830 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14204869 | 0.86 | THRA (0.57) | ALDH1A1MEN1KMT2AKDM4ETHRA | |
| SCHEMBL4730730 | 0.84 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2AKDM4ETHRA | |
| SCHEMBL4729035 | 0.81 | MEN1 (0.47) | ALDH1A1MEN1KMT2AKDM4ETSHR | |
| SCHEMBL4782911 | 0.80 | MEN1 (0.46) | ALDH1A1MEN1KMT2AKDM4ETHRA | |
| SCHEMBL4728149 | 0.79 | HPGD (0.55) | ALDH1A1MEN1KMT2ATSHRLMNA | |
| SCHEMBL14203260 | 0.79 | KMT2A (0.48) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL14203242 | 0.77 | CREBBP (0.46) | ALDH1A1KMT2AKDM4ETHRATHRB | |
| SCHEMBL12417592 | 0.75 | ALDH1A1 (0.86) | ALDH1A1MEN1KMT2AKDM4ETSHR | |
| SCHEMBL13886370 | 0.74 | MEN1 (0.49) | ALDH1A1MEN1KMT2AKDM4ETAS1R3 | |
| SCHEMBL1021602 | 0.74 | MAPT (0.56) | ALDH1A1MEN1KMT2ATSHRTAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008052288-A1 | DITHIOLE COMPOUNDS AS COX INHIBITORS | NEURO THERAPEUTICS LIMITED (AU) | 2008-05-08 | — | — | WO | disclosed |
| WO-2008052288-A1 | DITHIOLE COMPOUNDS AS COX INHIBITORS | NEURO THERAPEUTICS LIMITED (AU) | 2008-05-08 | — | — | WO | disclosed |