SCHEMBL16307662

SCHEMBL16307662

CCOC(=O)[C@@H]1C[N@@]1CCC[Si](OCC)(OCC)OCC

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.35
KMT2A Q03164 2/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 3/20 0.32
FKBP1A P62942 2/20 0.32
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15032478 1.00 ALDH1A1 (0.35) ALDH1A1KMT2ALMNAMAPTFKBP1A
SCHEMBL15025630 0.92 HPGD (0.31)
SCHEMBL16283147 0.92 HPGD (0.31)
SCHEMBL1144589 0.88 CYP3A4 (0.32) MAPTFKBP1A
SCHEMBL16307235 0.87 ALDH1A1 (0.34) ALDH1A1KMT2ALMNAMAPTFKBP1A
SCHEMBL15025583 0.86 L3MBTL1 (0.34) ALDH1A1KMT2ALMNAKDM4EMEN1
SCHEMBL16281911 0.86
SCHEMBL16133377 0.82 ALDH1A1 (0.47) ALDH1A1KMT2ALMNAMAPTFKBP1A
SCHEMBL11588481 0.73 MAPT (0.40) ALDH1A1KMT2ALMNAMAPTFKBP1A
SCHEMBL15025628 0.73 MEN1 (0.41) ALDH1A1KMT2AFKBP1AKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140371392-A1 Polymeric Materials Modified By Silanes DOW CORNING EUROPE S.A. (BE) 2014-12-18 US disclosed