Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 7/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 7/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 7/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 7/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 7/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 7/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 7/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 7/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727027 | 0.91 | MARS1 (0.42) | MARS1ALPLPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL4729857 | 0.86 | PRKAB2 (0.47) | MARS1ALPLPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL4731047 | 0.85 | MAPT (0.43) | ALPLMAPTHPGD | |
| SCHEMBL4728060 | 0.81 | ALPL (0.43) | MARS1ALPLPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL4727651 | 0.79 | MARS1 (0.43) | MARS1ALPLPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL4779778 | 0.78 | ALPL (0.40) | MARS1ALPLPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL4730399 | 0.78 | ALPL (0.40) | MARS1ALPLPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL4730236 | 0.77 | ESRRB (0.39) | MARS1ALPLPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL4784484 | 0.77 | MAPT (0.41) | ALPLMAPTHPGD | |
| SCHEMBL4726990 | 0.76 | PDGFRB (0.40) | MARS1ALPLPRKAB2PRKAG1PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |