Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732282 | 0.92 | KDM4E (0.32) | IRAK4MAPT | |
| SCHEMBL4731299 | 0.92 | APOBEC3A (0.35) | — | |
| SCHEMBL4727903 | 0.88 | MAPT (0.39) | MAPT | |
| SCHEMBL4730446 | 0.86 | KDM4E (0.38) | MAPT | |
| SCHEMBL4731297 | 0.86 | TP53 (0.34) | MAPT | |
| SCHEMBL4731374 | 0.85 | NTRK1 (0.34) | MAPT | |
| SCHEMBL4732555 | 0.84 | APOBEC3A (0.34) | — | |
| SCHEMBL4140062 | 0.81 | KDM4E (0.38) | MAPT | |
| SCHEMBL4140069 | 0.81 | KDM4E (0.38) | MAPT | |
| SCHEMBL4732771 | 0.79 | APOBEC3A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008043791-A2 | THIOPHENE DERIVATIVES FOR TREATING HEPATITIS C | SMITHKLINE BEECHAM CORPORATION (US) | 2008-04-17 | — | — | WO | disclosed |
| WO-2008043791-A2 | THIOPHENE DERIVATIVES FOR TREATING HEPATITIS C | SMITHKLINE BEECHAM CORPORATION (US) | 2008-04-17 | — | — | WO | disclosed |