Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | NNMT | P40261 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731307 | 0.80 | CETP (0.44) | TACR1CCR2 | |
| SCHEMBL4731572 | 0.80 | PSEN1 (0.39) | TACR1GPBAR1 | |
| SCHEMBL4728949 | 0.79 | TACR1 (0.35) | TACR1TP53CYP2D6TSHRSLC6A2 | |
| SCHEMBL4731680 | 0.79 | CETP (0.43) | TACR1CCR2 | |
| SCHEMBL4732423 | 0.79 | CETP (0.41) | TACR1 | |
| SCHEMBL4732645 | 0.78 | CCR2 (0.42) | TACR1CCR2SLC6A2SLC6A4 | |
| SCHEMBL3998806 | 0.77 | TACR1 (0.34) | TACR1ARCYP2D6TSHRSLC6A2 | |
| SCHEMBL4731447 | 0.77 | PTGDR2 (0.42) | TACR1TP53CYP2C19 | |
| SCHEMBL4731356 | 0.74 | TACR1 (0.44) | TACR1CCR2NPC1USP2ALDH1A1 | |
| SCHEMBL4731663 | 0.74 | TACR1 (0.40) | TACR1TP53POLBSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008045564-A2 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF THE CHEMOKINE CCR2 RECEPTOR | EPIX DELAWARE, INC. (US) | 2008-04-17 | — | — | WO | claimed |