Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 2/20 | 0.37 |
| ▸ | LDHB | P07195 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731307 | 0.78 | CETP (0.44) | TACR1 | |
| SCHEMBL4731572 | 0.78 | PSEN1 (0.39) | TACR1 | |
| SCHEMBL4728949 | 0.77 | TACR1 (0.35) | TP53TACR1 | |
| SCHEMBL4732423 | 0.77 | CETP (0.41) | TACR1 | |
| SCHEMBL4731680 | 0.77 | CETP (0.43) | TACR1 | |
| SCHEMBL4731354 | 0.77 | TACR1 (0.40) | CYP2C19TP53TACR1 | |
| SCHEMBL3023285 | 0.74 | PTGER4 (0.44) | CYP2C9CYP2C19PTGER4EPHX2NR1H4 | |
| SCHEMBL3998806 | 0.73 | TACR1 (0.34) | TACR1 | |
| SCHEMBL4732645 | 0.73 | CCR2 (0.42) | TACR1 | |
| SCHEMBL4731791 | 0.73 | CETP (0.40) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008045564-A2 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF THE CHEMOKINE CCR2 RECEPTOR | EPIX DELAWARE, INC. (US) | 2008-04-17 | — | — | WO | claimed |