Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 12/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731307 | 0.79 | CETP (0.44) | TACR1CETP | |
| SCHEMBL4731354 | 0.79 | TACR1 (0.40) | TACR1TSHRSLC6A2SLC6A4CYP2D6 | |
| SCHEMBL4731572 | 0.79 | PSEN1 (0.39) | TACR1CETP | |
| SCHEMBL4732423 | 0.78 | CETP (0.41) | TACR1CETP | |
| SCHEMBL4731680 | 0.78 | CETP (0.43) | TACR1CETP | |
| SCHEMBL4731447 | 0.77 | PTGDR2 (0.42) | TACR1TP53 | |
| SCHEMBL4732645 | 0.77 | CCR2 (0.42) | TACR1SLC6A2SLC6A4 | |
| SCHEMBL3998806 | 0.76 | TACR1 (0.34) | TACR1TSHRSLC6A2SLC6A4CYP2D6 | |
| SCHEMBL4731663 | 0.73 | TACR1 (0.40) | TACR1SLC6A2SLC6A4TP53 | |
| SCHEMBL4731791 | 0.73 | CETP (0.40) | TACR1SLC6A2SLC6A4CYP2D6CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008045564-A2 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF THE CHEMOKINE CCR2 RECEPTOR | EPIX DELAWARE, INC. (US) | 2008-04-17 | — | — | WO | disclosed |