Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 7/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734759 | 0.86 | MEN1 (0.45) | MEN1KMT2A | |
| SCHEMBL4729666 | 0.85 | MEN1 (0.44) | MEN1KMT2APRMT5WDR77KDM4E | |
| SCHEMBL4733900 | 0.85 | ALDH1A1 (0.41) | MEN1KMT2AKDM4EMAPT | |
| SCHEMBL4798309 | 0.85 | MEN1 (0.44) | MEN1KMT2APRMT5WDR77KDM4E | |
| SCHEMBL4734712 | 0.84 | POLB (0.46) | PRMT5WDR77 | |
| SCHEMBL4733520 | 0.78 | MEN1 (0.48) | MEN1KMT2APRMT5WDR77KDM4E | |
| SCHEMBL4732674 | 0.76 | ALOX5AP (0.34) | KDM4E | |
| SCHEMBL4730924 | 0.75 | ALDH1A1 (0.32) | — | |
| SCHEMBL4733963 | 0.74 | CNR2 (0.38) | MEN1KMT2A | |
| SCHEMBL4731333 | 0.73 | PRMT5 (0.46) | MEN1KMT2APRMT5WDR77KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | claimed |
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |