Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SFRP1 | Q8N474 | 14/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 5/20 | 0.43 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.43 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.43 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731611 | 0.89 | SFRP1 (0.69) | SFRP1EPHX2 | |
| SCHEMBL4737077 | 0.88 | SFRP1 (0.68) | SFRP1EPHX2 | |
| SCHEMBL4735165 | 0.87 | SFRP1 (0.67) | SFRP1EPHX2 | |
| SCHEMBL4734932 | 0.86 | SFRP1 (0.62) | SFRP1EPHX2 | |
| SCHEMBL4732405 | 0.85 | SFRP1 (0.77) | SFRP1EPHX2 | |
| SCHEMBL4734320 | 0.85 | SFRP1 (0.64) | SFRP1EPHX2 | |
| SCHEMBL4734362 | 0.85 | SFRP1 (0.64) | SFRP1EPHX2 | |
| SCHEMBL4733575 | 0.85 | SFRP1 (0.71) | SFRP1EPHX2 | |
| SCHEMBL4733299 | 0.85 | SFRP1 (0.64) | SFRP1EPHX2 | |
| SCHEMBL4732579 | 0.83 | SFRP1 (0.88) | SFRP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | claimed |
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |