Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733257 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL4732201 | 0.86 | LMNA (0.42) | ALDH1A1HPGDTDP1RAB9ALMNA | |
| SCHEMBL4732195 | 0.86 | LMNA (0.42) | ALDH1A1HPGDTDP1RAB9ALMNA | |
| SCHEMBL4733252 | 0.85 | CCNE2 (0.41) | SMN1; SMN2ALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL8160928 | 0.76 | TDP1 (0.47) | SMN1; SMN2ALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL8160923 | 0.76 | TDP1 (0.47) | SMN1; SMN2ALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL4015579 | 0.76 | HPGD (0.46) | SMN1; SMN2ALDH1A1HPGDTDP1RAB9A | |
| Metacresol SCHEMBL11774925 | 0.74 | ACHE (0.44) | SMN1; SMN2ALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL7723603 | 0.73 | PARP1 (0.61) | SMN1; SMN2ALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL7723600 | 0.73 | PARP1 (0.61) | SMN1; SMN2ALDH1A1MAPTHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008057705-A1 | FOAMED PLASTIC STRUCTURES | NOVA CHEMICALS INC. (US) | 2008-05-15 | — | — | WO | disclosed |