Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | IKBKB | O14920 | 2/20 | 0.44 |
| ▸ | QPCT | Q16769 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729681 | 0.81 | CYP3A4 (0.52) | KMT2AALDH1A1 | |
| SCHEMBL4733867 | 0.80 | MEN1 (0.46) | KMT2ALMNAALDH1A1 | |
| SCHEMBL4730716 | 0.78 | SLC2A1 (0.45) | ALDH1A1 | |
| SCHEMBL4732610 | 0.78 | NR2F2 (0.51) | LMNAALDH1A1 | |
| SCHEMBL4731712 | 0.77 | ALDH1A1 (0.51) | KMT2AALDH1A1 | |
| SCHEMBL4636839 | 0.76 | CYP19A1 (0.71) | CYP19A1KMT2ALMNAALDH1A1IKBKB | |
| SCHEMBL4731333 | 0.76 | PRMT5 (0.46) | KMT2AALDH1A1 | |
| SCHEMBL4730919 | 0.75 | POLB (0.58) | KMT2AALDH1A1 | |
| SCHEMBL4734747 | 0.75 | KMT2A (0.48) | KMT2ALMNAALDH1A1 | |
| SCHEMBL4637595 | 0.74 | KMT2A (0.70) | CYP19A1KMT2ALMNAALDH1A1QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | claimed |
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |