Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 10/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.39 |
| ▸ | RELA | Q04206 | 4/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729890 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2FABP4FABP3TDP1L3MBTL1 | |
| SCHEMBL8203895 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2FABP4FABP3TDP1L3MBTL1 | |
| SCHEMBL4731714 | 0.89 | TDP1 (0.40) | FABP4FABP3TDP1L3MBTL1NFKB1 | |
| SCHEMBL4732072 | 0.89 | TDP1 (0.40) | FABP4FABP3TDP1L3MBTL1NFKB1 | |
| SCHEMBL4732206 | 0.85 | L3MBTL1 (0.42) | SMN1; SMN2FABP4FABP3TDP1L3MBTL1 | |
| SCHEMBL5324235 | 0.79 | TDP1 (0.39) | FABP4FABP3TDP1L3MBTL1 | |
| SCHEMBL5324231 | 0.78 | NFKB1 (0.46) | TDP1L3MBTL1NFKB1NFKB2RELA | |
| SCHEMBL4732706 | 0.77 | SMN1; SMN2 (0.46) | SMN1; SMN2 | |
| SCHEMBL8202534 | 0.77 | SMN1; SMN2 (0.46) | SMN1; SMN2 | |
| SCHEMBL23911581 | 0.76 | NFKB1 (0.41) | SMN1; SMN2NFKB1NFKB2RELALTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008052088-A1 | CHROMANE DERIVATIVES, SYNTHESIS THEREOF, AND INTERMEDIATES THERETO | WYETH (US) | 2008-05-02 | — | — | WO | disclosed |