Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.43 |
| ▸ | TERT | O14746 | 4/20 | 0.42 |
| ▸ | CYCS | P99999 | 3/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | ADK | P55263 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1410189 | 0.87 | CYCS (0.36) | TOP1TERTCYCS | |
| SCHEMBL2963039 | 0.85 | STAT3 (0.50) | TOP1TERTCYCSMTORADK | |
| SCHEMBL2955031 | 0.81 | STAT3 (0.52) | TOP1CYCSMTORADKNISCH | |
| SCHEMBL3520923 | 0.76 | STAT3 (0.42) | TERT | |
| SCHEMBL6393633 | 0.70 | TERT (0.45) | TOP1TERTCYCS | |
| SCHEMBL2963034 | 0.70 | NISCH (0.36) | MTORADKNISCH | |
| SCHEMBL29822398 | 0.69 | KDM4E (0.46) | TOP1TERTMTOR | |
| SCHEMBL432185 | 0.69 | KDM4E (0.46) | TOP1TERTMTOR | |
| SCHEMBL5918783 | 0.69 | TERT (0.44) | TOP1TERTCYCS | |
| SCHEMBL245937 | 0.68 | TOP1 (0.78) | TOP1TERTCYCS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8334377-B2 | Porphyrin catalysts and methods of use thereof | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2012-12-18 | — | — | US | disclosed |
| US-20110306584-A1 | Porphyrin Catalysts and Methods of Use Thereof | TRUSTEES OF PRINCETON (US) | 2011-12-15 | — | — | US | disclosed |
| WO-2008045358-A1 | PORPHYRIN CATALYSTS AND METHODS OF USE THEREOF | TRUSTEES OF PRINCETON (US) | 2008-04-17 | — | — | WO | disclosed |
| US-7245851-B2 | Electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2007-07-17 | — | — | US | disclosed |
| US-7245851-B2 | Electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2007-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110306584-A1 | Porphyrin Catalysts and Methods of Use Thereof | PPOX, POR, MPO | TOP1 1772/4885TERT 1434/4885CYCS 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.