Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 5/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 7/20 | 0.33 |
| ▸ | MELK | Q14680 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.32 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13132264 | 0.79 | REN (0.46) | RENKMOADORA2AADORA2BGLS | |
| SCHEMBL91359 | 0.79 | REN (0.46) | RENKMOADORA2AADORA2BGLS | |
| SCHEMBL4732483 | 0.78 | REN (0.40) | RENHRH3SLC22A12 | |
| SCHEMBL1051150 | 0.76 | REN (0.45) | RENKMOADORA2AADORA2BGLS | |
| SCHEMBL4249553 | 0.76 | REN (0.45) | RENKMOADORA2AADORA2BGLS | |
| SCHEMBL13448565 | 0.76 | REN (0.45) | RENKMOADORA2AADORA2BGLS | |
| SCHEMBL13131423 | 0.75 | ADORA2A (0.44) | RENKMOADORA2AADORA2BGLS | |
| SCHEMBL78153 | 0.74 | REN (0.55) | RENKMOADORA2AADORA2BGLS | |
| SCHEMBL4253933 | 0.74 | REN (0.45) | RENKMOADORA2AADORA2BGLS | |
| SCHEMBL2807350 | 0.74 | REN (0.48) | RENKMOSLC22A12NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008055939-A2 | PROCESS FOR PREPARING 2-ALKYL-3-HETEROCYCLYL- PROP-2-EN- 1-OL DERIVATIVES | NOVARTIS AG (CH) | 2008-05-15 | — | — | WO | disclosed |