Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | F2R | P25116 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28429236 | 0.83 | F2R (0.51) | ALDH1A1KDM4ELMNAHPGDTSHR | |
| SCHEMBL4732713 | 0.79 | KDM4E (0.54) | ALDH1A1KDM4ELMNAHPGDTSHR | |
| SCHEMBL5928724 | 0.76 | TSHR (0.68) | ALDH1A1KDM4ELMNAHPGDTSHR | |
| SCHEMBL2624140 | 0.73 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNAHPGDTSHR | |
| SCHEMBL10397861 | 0.72 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL1956734 | 0.72 | LMNA (0.63) | ALDH1A1KDM4ELMNATSHRKMT2A | |
| SCHEMBL24963554 | 0.71 | KMT2A (0.51) | ALDH1A1KDM4EHPGDTSHRHTT | |
| SCHEMBL2148841 | 0.71 | LMNA (0.57) | ALDH1A1KDM4ELMNATSHRKMT2A | |
| SCHEMBL16953017 | 0.71 | LMNA (0.52) | ALDH1A1KDM4ELMNATSHRKMT2A | |
| SCHEMBL28769090 | 0.70 | CA1 (0.59) | ALDH1A1KDM4ELMNATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008054454-A2 | NITROGEN-CONTAINING HETEROCYCLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF AS ANTIVIRAL AGENTS | TRANSTECH PHARMA, INC. (US) | 2008-05-08 | — | — | WO | disclosed |