Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15334365 | 0.86 | GAA (0.52) | KMT2AMAPTHPGDMEN1LMNA | |
| SCHEMBL4733 | 0.86 | CYP1A2 (0.55) | KMT2AMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL4077327 | 0.85 | KMT2A (0.49) | KMT2AMAPTLMNACYP4Z1MGAM | |
| SCHEMBL7960432 | 0.84 | L3MBTL1 (0.53) | KMT2AALDH1A1HPGDMEN1LMNA | |
| SCHEMBL15964601 | 0.84 | KMT2A (0.49) | KMT2AMAPTALDH1A1MEN1MAPK1 | |
| SCHEMBL622329 | 0.83 | MAPT (0.61) | KMT2AMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL14390296 | 0.83 | CYP4Z1 (0.46) | KMT2AMAPTALDH1A1MEN1LMNA | |
| SCHEMBL21572817 | 0.83 | CYP4Z1 (0.46) | KMT2AMAPTALDH1A1MEN1LMNA | |
| SCHEMBL699965 | 0.83 | KDM4E (0.50) | KMT2AMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL319873 | 0.83 | PPID (0.54) | KMT2AALDH1A1MEN1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3529250-B1 | IMIDAZOPYRAZINONES, PYRAZOLOPYRIMIDINONES AND PYRAZOLOPYRIDINONES AS PDE1 INHIBITORS | H LUNDBECK AS (DK) | 2023-12-06 | — | — | EP | disclosed |
| CN-111467346-B | Pyridone derivatives with tetrahydropyranylmethyl groups | 第一三共株式会社 | 2023-05-16 | — | — | CN | disclosed |
| CN-109843884-B | Imidazopyrazinones, pyrazolopyrimidinones and pyrazolopyridinones as PDE1 inhibitors | H.隆德贝克有限公司 | 2022-03-04 | — | — | CN | disclosed |
| US-20220002277-A1 | PYRIDONE DERIVATIVE HAVING TETRAHYDROPYRANYLMETHYL GROUP | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2022-01-06 | — | — | US | disclosed |
| US-11208403-B2 | Pyridone derivatives having tetrahydropyranylmethyl groups | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-12-28 | — | — | US | disclosed |
| CN-110036014-B | Compound with AXL inhibitory activity and preparation and application thereof | 中国科学院上海药物研究所 | 2021-09-07 | — | — | CN | disclosed |
| US-20210171503-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | ORFAN BIOTECH SL (ES) | 2021-06-10 | — | — | US | disclosed |
| EP-3168219-B1 | PYRIDONE DERIVATIVE HAVING TETRAHYDROPYRANYL METHYL GROUP | DAIICHI SANKYO CO LTD (JP) | 2021-03-31 | — | — | EP | disclosed |
| EP-3731840-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | Orfan Biotech Inc. (US) | 2020-11-04 | — | — | EP | disclosed |
| CN-111467346-A | Pyridone derivatives with tetrahydropyranylmethyl groups | 第一三共株式会社 | 2020-07-31 | — | — | CN | disclosed |
| EP-1349843-B1 | THIAZOLE AND OXAZOLE DERIVATIVES AS ACTIVATORS OF HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | SMITHKLINE BEECHAM CORP (US) | 2005-04-20 | — | — | EP | disclosed |
| US-20040072838-A1 | Thiazole and oxazole derivatives as activators of human peroxisome proliferator activated receptors | SMITHKLINE BEECHAM CORPORATION | 2004-04-15 | — | — | US | disclosed |
| EP-1349843-A1 | THIAZOLE AND OXAZOLE DERIVATIVES AS ACTIVATORS OF HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | GLAXO GROUP LIMITED (GB) | 2003-10-08 | — | — | EP | disclosed |
| WO-2002059098-A1 | THIAZOLE AND OXAZOLE DERIVATIVES AS ACTIVATORS OF HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | GLAXO GROUP LIMITED (GB) | 2002-08-01 | — | — | WO | disclosed |
| US-5827863-A | Pyrazole derivatives as angiotensin II antagonists | J. URIACH & CIA, S.A. (ES) | 1998-10-27 | — | — | US | disclosed |
| US-5712296-A | Substituted pyridines and 2-oxo-1,2-dihydropyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1998-01-27 | — | — | US | disclosed |
| EP-0721454-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA. S.A. (ES) | 1996-07-17 | — | — | EP | disclosed |
| US-5492923-A | DRUG FOR TREATING ARTERIAL HYPERTENSION AND ATHEROSCLEROSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-02-20 | — | — | US | disclosed |
| WO-1996004273-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA, S.A. (ES) | 1996-02-15 | — | — | WO | disclosed |
| EP-0623610-A1 | Substituted pyridines and 2-oxo-1,2-dihydropyridines as Angiotensine II antagonists | BAYER AG (DE) | 1994-11-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220002277-A1 | PYRIDONE DERIVATIVE HAVING TETRAHYDROPYRANYLMETHYL GROUP | AXL, TYRO3, LCK | KMT2A 2465/4885MAPT 2529/4885ALDH1A1 4480/4885 |
| US-20040072838-A1 | Thiazole and oxazole derivatives as activators of human peroxisome proliferator activated receptors | PPARA, PPARG, PPARD | KMT2A 3950/4885MAPT 4132/4885ALDH1A1 1168/4885 |
| US-11208403-B2 | Pyridone derivatives having tetrahydropyranylmethyl groups | AXL, TYRO3, PDXK | KMT2A 2843/4885MAPT 2654/4885ALDH1A1 4318/4885 |
| US-20210171503-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | PNPO, XDH, GLS | KMT2A 3407/4885MAPT 2376/4885ALDH1A1 149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.