SCHEMBL4733137

SCHEMBL4733137

O=C(OCCc1ccccc1)c1cc(O)c(O)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 1.00
TYR P14679 3/20 0.77
SERPINE1 P05121 4/20 0.71
ESR1 P03372 2/20 0.67
ESR2 Q92731 1/20 0.67
NPC1 O15118 1/20 0.60
RAB9A P51151 1/20 0.60
NSD2 O96028 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4735890 0.91 L3MBTL1 (0.83) L3MBTL1TYRSERPINE1ESR1ESR2
SCHEMBL4738037 0.89 L3MBTL1 (0.81) L3MBTL1TYRSERPINE1ESR1
SCHEMBL4731853 0.88 L3MBTL1 (0.78) L3MBTL1TYRSERPINE1ESR1
SCHEMBL4738028 0.87 TYR (1.00) L3MBTL1TYRSERPINE1ESR1ESR2
SCHEMBL10726700 0.86 L3MBTL1 (0.75) L3MBTL1TYRESR1ESR2NPC1
SCHEMBL30674459 0.86 L3MBTL1 (0.75) L3MBTL1TYRESR1ESR2NPC1
Propyl Gallate SCHEMBL28582966 0.84 L3MBTL1 (0.72) L3MBTL1TYRSERPINE1ESR1
SCHEMBL9838369 0.84 TYR (0.78) L3MBTL1TYRSERPINE1ESR1NPC1
SCHEMBL2791373 0.84 SERPINE1 (1.00) L3MBTL1TYRSERPINE1ESR1
SCHEMBL1347680 0.83 L3MBTL1 (0.71) L3MBTL1TYRSERPINE1NSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240425441-A9 MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY ICOSA PHARMA INC. (CA) 2024-12-26 US claimed
US-20230391711-A1 MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY UNIV DE MONCTON (CA) 2023-12-07 US claimed
EP-3423429-B1 MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY UNIV DE MONCTON (CA) 2023-07-12 EP claimed
US-20190119194-A1 MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY UNIVERSITE DE MONCTON (CA) 2019-04-25 US claimed
US-20240425441-A9 MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY ICOSA PHARMA INC. (CA) 2024-12-26 US disclosed
US-20230391711-A1 MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY UNIV DE MONCTON (CA) 2023-12-07 US disclosed
EP-4276089-A2 MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY Universite De Moncton (CA) 2023-11-15 EP disclosed
EP-4276089-A2 MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY Universite De Moncton (CA) 2023-11-15 EP disclosed
US-11760715-B2 Modulators of lipoxygenase and cyclooxygenase enzyme activity UNIVERSITÉ DE MONCTON (CA) 2023-09-19 US disclosed
US-11760715-B2 Modulators of lipoxygenase and cyclooxygenase enzyme activity UNIVERSITÉ DE MONCTON (CA) 2023-09-19 US disclosed
US-11760715-B2 Modulators of lipoxygenase and cyclooxygenase enzyme activity UNIVERSITÉ DE MONCTON (CA) 2023-09-19 US disclosed
EP-3423429-B1 MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY UNIV DE MONCTON (CA) 2023-07-12 EP disclosed
EP-3423429-B1 MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY UNIV DE MONCTON (CA) 2023-07-12 EP disclosed
US-20190119194-A1 MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY UNIVERSITE DE MONCTON (CA) 2019-04-25 US disclosed
US-20190119194-A1 MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY UNIVERSITE DE MONCTON (CA) 2019-04-25 US disclosed
WO-2008065527-A2 GALLIC ACID ESTERS OF FRAGRANT ALCOHOLS GHISALBERTI CARLO (BR) 2008-06-05 WO disclosed
US-5084593-A Cyanine, aniline dyes for heat sensitive recording elements RICOH COMPANY, LTD. (JP) 1992-01-28 US disclosed
US-5008238-A Thermosensitive material with phenolic developer RICOH COMPANY, LTD. (JP) 1991-04-16 US disclosed
US-4418037-A PYROGALLOL DERIVATIVE STORAGE STABILIZER FUJI PHOTO FILM CO., LTD. (JP) 1983-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240425441-A9 MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY ALOX12, ALOX15B, ALOX5 L3MBTL1 2703/4885TYR 918/4885SERPINE1 736/4885
US-11760715-B2 Modulators of lipoxygenase and cyclooxygenase enzyme activity ALOX12, ALOX15B, ALOX5 L3MBTL1 2703/4885TYR 918/4885SERPINE1 736/4885
US-20190119194-A1 MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY ALOX12, ALOX15B, ALOX5 L3MBTL1 2703/4885TYR 918/4885SERPINE1 736/4885
US-20230391711-A1 MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY ALOX12, ALOX15B, ALOX5 L3MBTL1 2703/4885TYR 918/4885SERPINE1 736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.