Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SFRP1 | Q8N474 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | CCR8 | P51685 | 9/20 | 0.38 |
| ▸ | WNT3 | P56703 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4730139 | 0.92 | SFRP1 (0.45) | SFRP1KMT2AMEN1CCR8WNT3 | |
| SCHEMBL4733197 | 0.90 | CCR8 (0.43) | KMT2AMEN1CCR8 | |
| SCHEMBL4730986 | 0.90 | SFRP1 (0.46) | SFRP1KMT2AMEN1CCR8WNT3 | |
| SCHEMBL4730495 | 0.83 | SFRP1 (0.50) | SFRP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL4730981 | 0.81 | SFRP1 (0.46) | SFRP1KMT2AMEN1WNT3HTR1A | |
| SCHEMBL4733195 | 0.81 | CCR8 (0.41) | KMT2AMEN1CCR8 | |
| SCHEMBL4734862 | 0.80 | MEN1 (0.41) | SFRP1KMT2AMEN1HTR1AHTR7 | |
| SCHEMBL4730903 | 0.79 | SFRP1 (0.44) | SFRP1KMT2AMEN1CCR8WNT3 | |
| SCHEMBL4730240 | 0.78 | CCR8 (0.39) | SFRP1KMT2AMEN1CCR8WNT3 | |
| SCHEMBL4784267 | 0.77 | SFRP1 (0.48) | SFRP1CCR8WNT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | claimed |
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |