Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4736542 | 0.89 | SMN1; SMN2 (0.58) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL4737383 | 0.78 | NPC1 (0.60) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL4737093 | 0.77 | RAB9A (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL4849787 | 0.76 | ALDH1A1 (0.53) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL4737760 | 0.75 | GRIK1 (0.57) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL4735004 | 0.75 | NPC1 (0.54) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL4738643 | 0.73 | ALDH1A1 (0.59) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL4957641 | 0.70 | ALDH1A1 (0.67) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL4736482 | 0.70 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL433102 | 0.70 | ALDH1A1 (1.00) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008069611-A1 | N-PHENYLAMIDE DERIVATIVE, PROCESS FOR THE PREPARATION THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING ISCHEMIC DISEASES COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-06-12 | — | — | WO | claimed |
| WO-2008069611-A1 | N-PHENYLAMIDE DERIVATIVE, PROCESS FOR THE PREPARATION THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING ISCHEMIC DISEASES COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-06-12 | — | — | WO | disclosed |