Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737594 | 0.87 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL4910948 | 0.85 | ALDH1A1 (0.34) | CYP1A1ALDH1A1DRD2DRD3KCNH2 | |
| SCHEMBL4735344 | 0.84 | ADORA2B (0.30) | ADORA2B | |
| SCHEMBL4733748 | 0.83 | — | — | |
| SCHEMBL4737143 | 0.80 | TDP1 (0.38) | ALDH1A1 | |
| SCHEMBL4805989 | 0.80 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL4785349 | 0.79 | BACE1 (0.46) | — | |
| SCHEMBL4906871 | 0.77 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL4738183 | 0.76 | MMP2 (0.33) | — | |
| SCHEMBL4734992 | 0.74 | MMP2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008076046-A1 | NOVEL 2-AMINO-5, 5-DIARYL-IMIDAZOL-4-ONES | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |