Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729697 | 0.95 | HCAR2 (0.37) | HCAR2TSHRALDH1A1 | |
| SCHEMBL466288 | 0.79 | NAAA (0.38) | HCAR2CES2NAAATSHRTP53 | |
| SCHEMBL1581516 | 0.77 | NAAA (0.41) | HCAR2CES2NAAATSHRRAD52 | |
| SCHEMBL4732012 | 0.76 | ALDH1A1 (0.30) | TSHRALDH1A1 | |
| SCHEMBL10481805 | 0.75 | ACLY (0.36) | HCAR2CYP3A4MAPK1EP300 | |
| SCHEMBL475085 | 0.73 | ALDH1A1 (0.39) | HCAR2TSHRTP53CYP3A4MAPK1 | |
| SCHEMBL4733464 | 0.72 | HCAR2 (0.37) | HCAR2CES2NAAATSHRS1PR1 | |
| Pivalate SCHEMBL27493603 | 0.70 | NAAA (0.43) | HCAR2CES2NAAATSHRTP53 | |
| SCHEMBL3624694 | 0.70 | RIPK1 (0.34) | TSHR | |
| SCHEMBL3624695 | 0.70 | RIPK1 (0.34) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008057705-A1 | FOAMED PLASTIC STRUCTURES | NOVA CHEMICALS INC. (US) | 2008-05-15 | — | — | WO | disclosed |