Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 8/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4730493 | 0.89 | ALDH1A1 (0.40) | PKMMGAM | |
| SCHEMBL4734133 | 0.87 | TBXAS1 (0.40) | TBXAS1POLBNPY5R | |
| SCHEMBL4730979 | 0.80 | TBXAS1 (0.42) | TBXAS1POLBNPY5R | |
| SCHEMBL4733942 | 0.79 | POLB (0.48) | TBXAS1POLBPRMT5WDR77 | |
| SCHEMBL4732031 | 0.76 | ALDH1A1 (0.41) | PKM | |
| SCHEMBL4732619 | 0.75 | TAAR1 (0.43) | POLB | |
| SCHEMBL4734755 | 0.75 | POLB (0.46) | TBXAS1POLBPKMNAMPTPRMT5 | |
| SCHEMBL4732410 | 0.75 | TBXAS1 (0.40) | TBXAS1POLBNAMPTPRMT5WDR77 | |
| SCHEMBL4796983 | 0.74 | SMN1; SMN2 (0.38) | TBXAS1POLBPRMT5WDR77NPY5R | |
| SCHEMBL4734005 | 0.74 | TBXAS1 (0.39) | TBXAS1POLBNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | claimed |
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |