Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.39 |
| ▸ | MLNR | O43193 | 8/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4738924 | 0.86 | OPRM1 (0.40) | MAPK14CXCR2KDM4EALDH1A1TSHR | |
| SCHEMBL4735426 | 0.86 | OPRM1 (0.43) | MAPK14CXCR2KDM4EALDH1A1TSHR | |
| SCHEMBL4733765 | 0.85 | CNR2 (0.36) | MAPK14MLNRCXCR2CNR2KDM4E | |
| SCHEMBL4737014 | 0.84 | HDAC2 (0.42) | MAPK14MLNRCXCR2KDM4EALDH1A1 | |
| SCHEMBL4735517 | 0.84 | MAPK14 (0.38) | MAPK14MLNRCXCR2KDM4EALDH1A1 | |
| SCHEMBL4737305 | 0.83 | DRD4 (0.45) | MAPK14CXCR2KDM4EALDH1A1TSHR | |
| SCHEMBL4733795 | 0.83 | KDM4E (0.51) | MAPK14CXCR2KDM4EALDH1A1TSHR | |
| SCHEMBL4738909 | 0.83 | TSHR (0.44) | MAPK14CXCR2KDM4EALDH1A1TSHR | |
| SCHEMBL4735512 | 0.81 | HRH3 (0.43) | MAPK14TSHRHSD17B10 | |
| SCHEMBL4733666 | 0.80 | OPRM1 (0.49) | MAPK14KDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |