Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | PARG | Q86W56 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 4/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732673 | 0.82 | CNR2 (0.40) | CNR2PKMMAOA | |
| SCHEMBL4733897 | 0.82 | CNR2 (0.40) | CNR2PKM | |
| SCHEMBL4732817 | 0.80 | CNR2 (0.39) | CNR2PKMMEN1KMT2AGAA | |
| SCHEMBL4733963 | 0.79 | CNR2 (0.38) | CNR2PKMMEN1KMT2AGAA | |
| SCHEMBL4730155 | 0.78 | CNR2 (0.39) | CNR2PKMGAANPSR1 | |
| SCHEMBL4732243 | 0.78 | CNR2 (0.39) | CNR2PKMALDH1A1GAANPSR1 | |
| SCHEMBL4732276 | 0.74 | CNR2 (0.41) | CNR2MEN1KMT2A | |
| SCHEMBL4618055 | 0.73 | GBA1 (0.50) | PARGCNR2PKMALDH1A1MEN1 | |
| SCHEMBL4733373 | 0.73 | BRD4 (0.40) | CNR2PKMALDH1A1MEN1KMT2A | |
| SCHEMBL4619103 | 0.70 | SFRP1 (0.58) | PARGCNR2PKMALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | claimed |
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |