Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4730155 | 0.99 | CNR2 (0.39) | CNR2PKMCNR1MITFBCL2L1 | |
| SCHEMBL4732817 | 0.87 | CNR2 (0.39) | CNR2PKMCNR1TSHRHTT | |
| SCHEMBL4732586 | 0.86 | HTT (0.38) | TSHRHTTLMNAGAANPSR1 | |
| SCHEMBL4733963 | 0.85 | CNR2 (0.38) | CNR2PKMCNR1TSHRHTT | |
| SCHEMBL4732186 | 0.85 | HTT (0.36) | TSHRHTTLMNAGAAALDH1A1 | |
| SCHEMBL4798089 | 0.83 | ALDH1A1 (0.37) | CNR2PKMLMNAALDH1A1GBA1 | |
| SCHEMBL4731973 | 0.81 | HPGD (0.39) | LMNAGAANPSR1ALDH1A1 | |
| SCHEMBL4799653 | 0.79 | PARG (0.35) | TSHRHTT | |
| SCHEMBL4734831 | 0.78 | PARG (0.36) | TSHRHTT | |
| SCHEMBL4733897 | 0.78 | CNR2 (0.40) | CNR2PKMCNR1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | claimed |
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |